Diagnosing ADHD Not an Exact #Science

ek-adhddiagnosis-articlelead-620x349By Amanda Mascarelli

Why is it still so hard to diagnose ADHD? And why is there so much emotional baggage associated with treating it? Photo: Getty Images

When my son was in preschool, I did what many parents of excessively energetic and impulsive preschoolers have surely done: I worried whether his behaviour might be a sign of attention-deficit hyperactivity disorder (ADHD). Then I sought input from two paediatricians and a family therapist.

The experts thought that his behaviour was developmentally normal but said it was still too early to tell for sure. They offered some tips on managing his behaviour and creating more structure at home. One paediatrician worked with my son on self-calming techniques such as breathing deeply and pushing on pressure points in his hands. He also suggested an herbal supplement, Valerian Super Calm, for him to take with meals and advised us on dietary adjustments such as increasing my son’s intake of fatty acids. Studies have shown that a combination of omega-3 (found in foods such as walnuts, flaxseed and salmon) and omega-6 fatty acids (from food oils such as canola and flax) can reduce hyperactivity and other ADHD symptoms in some children.

In the couple of years since trying these techniques, my son has outgrown most of those worrisome behaviours. I had just about written off the possibility of ADHD until a few weeks ago, when his kindergarten teacher mentioned that she was going to keep an eye on him for possible attention issues. Hearing that left me worried and heavy-hearted.

Why is it still so hard to diagnose ADHD? And why is there so much emotional baggage associated with treating it.

ADHD is far more prevalent in boys than in girls. Among those given the diagnosis, a small minority suffers extreme symptoms, and in those cases, diagnosis is fairly straightforward. Children with extreme cases tend to have trouble staying engaged in tasks, even those that they enjoy, for any length of time and find it impossible to stay still, particularly in classroom settings.

But for the vast majority of children who are not so severely affected or who only partially fit the criteria, symptoms are often blurred, making it much more difficult to assess the disorder.

“There is no line” that defines who does and does not have ADHD, says Lawrence Diller, a behavioural developmental paediatrician and an assistant clinical professor at the University of California at San Francisco. Except in the extreme, diagnosing ADHD is a “judgment call based on subjective opinion,” he says.

Diller recommends that parents first address discipline and learning issues before turning to medications, particularly in children younger than 6. He shows parents how to be more immediate with setting limits, such as using a timer to let kids know how long they can play or being clear about consequences (for instance, if cleanup isn’t sufficient, toys are removed immediately for a brief period of time), and he recommends “1-2-3 Magic,” a book that gives parents tools for effective discipline.

For “the kids who are in this gray zone, it can be difficult,” says Thomas Insel, director of the National Institute of Mental Health. “What we usually say is to err on the side of trying to provide kids with structure and feedback. If that doesn’t help, then you think about medication.”

Researchers are beginning to understand the neural pathways that underlie ADHD, progress that is identifying potential new strategies for treatment.

One promising area of research has found that dopamine, a chemical messenger in the brain commonly associated with motivation and reward, is reduced in adults with ADHD. (Such studies have not been done in children since they require the use of small amounts of radioactivity, which is not recommended for people younger than 18.)

In a 2009 study in the Journal of the American Medical Association, a team led by Nora Volkow, director of the National Institute on Drug Abuse, reported that decreased dopamine signalling in the ventral striatum, an area of the brain involved with reward and motivation, was associated with attention problems in adults with untreated ADHD. The results suggest that low dopamine levels in the reward centre might explain why many children and adults with ADHD struggle with a lack of motivation about certain tasks.

In a 2012 study in the Journal of Neuroscience, Volkow and colleagues showed that methylphenidate, a stimulant that is the active ingredient in Concerta and Ritalin, restored dopamine to normal levels and significantly improved inattention and hyperactivity in adults. Notably, they found that the dopamine messages were enhanced in the ventral striatum following treatment. This showed that increased dopamine transmission in the reward centre of the brain was key to improving their patients’ ADHD symptoms.

Even though stimulants have been proved safe and effective in children with ADHD, the decision to medicate is controversial and fraught with anxiety for many parents.

“We just tend to fight against” treating a disorder whose diagnosis is based on behavioural symptoms, Insel says. He emphasizes that behavioural interventions should be tried first in those with moderate symptoms but says that medication can be remarkably helpful for children with the disorder.

Deferring treatment for children who need help can have serious consequences, he notes; self-esteem begins to suffer because the children are constantly being corrected for not sitting still or paying attention. “The cost of not doing something about it becomes more severe,” Insel says.

Even if your child is identified as having ADHD, it remains an open question whether he will outgrow the diagnosis. A 2013 study in the journal Pediatrics found that just 30 percent of people who had received such diagnoses as children still had symptoms as adults. But other research has shown that the number is as high as 65 percent.

In our case, we plan to observe our son closely and stay in touch with the teacher, but we don’t yet have major concerns. He’s happy in school and progressing well. But as any parent surely understands, it can be nerve-racking to wait and see, especially when a child’s well-being is at stake.

– © Fairfax NZ News



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